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Electrophoretic Tissue Clearing (ETC)
Anyone consider using the X-CLARITY instrument?
I'm surprised I haven't seen any discussion of X-CLARITY here. I was wondering what people think about it... Have you heard of it? Have you thought about using it?
I have used the X-CLARITY for clearing mouse brains. According to the company, it works well on various mouse tissues. Even bone. Easy to use and never fail for me. In addition, scientists at that company recently published a paper in Scientific Reports (
). As far as I know, the company provides a free demo for a while. I think, this demo will be helpful for you guys.
I've used XCLARITY. It has good performance. While I accept it was expansive than home made CLRITY, I think it deserved cause easy to use and getting fast results.
X-CLARITY from Logos Biosystems will make your life easy. there is just released the 2nd generation of X-CLARUTY divice (ETC2 systems).
Try SmartClear from LifeCanvas Technologies (
) instead! This is what the D Lab at Stanford uses (3 of them in fact) and the company is now offering a free clearing and imaging service as well!